Vitamin B12 or folate deficiency anaemia - NHS

Learn about the symptoms, causes, diagnosis and treatment of this condition that affects the red blood cells and the nervous system. Find out how to prevent and manage complications such as infertility, heart problems and birth defects.

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B12 and folate deficiency | Health topics A to Z | CKS - NICE

Treatment of B12 deficiency in people with neurologic involvement should include: Seeking urgent specialist advice from a haematologist. If specialist advice is not immediately available, initially treating with hydroxocobalamin 1 mg intramuscularly on alternate days until there is no further improvement, then hydroxocobalamin 1 mg intramuscularly every 2 months should be considered.

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Vitamin B12 Deficiency: Symptoms, Causes & Treatment - Cleveland Clinic

Learn about vitamin B12 deficiency, a condition that happens when your body doesn't get enough or absorb enough vitamin B12 from your diet. Find out the symptoms, causes, diagnosis, treatment and prevention of this nutritional deficiency.

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Vitamin B12 or folate deficiency anaemia - NHS inform

Functional vitamin B12 deficiency. Some people can experience problems related to a vitamin B12 deficiency, despite appearing to have normal levels of vitamin B12 in their blood. This can occur due to a problem known as functional vitamin B12 deficiency – where there’s a problem with the proteins that help transport vitamin B12 between cells.

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Vitamin B12 deficiency: NICE guideline summary - The BMJ

Learn about the symptoms, signs, risk factors, and testing strategies for vitamin B12 deficiency, a complex condition that can cause various complications. The guideline also covers the oral replacement dosage and monitoring of people with deficiency caused by malabsorption.

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Vitamin B12 Deficiency: Causes, Symptoms, and Treatment - WebMD

Vitamin B12 deficiency is associated with cognitive problems (problems with thinking, judgment, and learning) and memory issues. So, it may play a role in conditions such as Alzheimer's disease ...

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Signs and Symptoms of Vitamin B12 Deficiency - Healthline

Learn about the signs and symptoms of low or deficient B12 levels, such as fatigue, pale skin, headaches, depression, and more. Find out the causes of B12 deficiency, how it's diagnosed, and how it's treated with supplements or injections.

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What is vitamin B12 and why do we need it? - BBC Food

What causes B12 deficiency? Pernicious anaemia (an autoimmune condition) is the most common cause of B12 deficiency.. Autoimmune conditions happen when the immune system mistakenly attacks its own ...

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Vitamin B12 deficiency - Wikipedia

Learn about the causes, symptoms, diagnosis and treatment of vitamin B12 deficiency, a condition that affects the blood, tissue and nervous system. Find out how to prevent and supplement vitamin B12, and how common it is in different populations.

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Vitamin B12 deficiency - GPnotebook

Learn about the causes, symptoms, diagnosis and treatment of vitamin B12 deficiency, a condition that affects the bone marrow and the nervous system. Find out how to interpret serum B12 levels, the role of oral and intramuscular supplementation, and the risk of cobalt allergy.

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Vitamin B12 deficiency

Learn about the causes, symptoms, diagnosis and treatment of vitamin B12 deficiency, a condition that affects the blood, tissue and nervous system. Find out how to prevent and supplement vitamin B12, and how common it is in different populations.

Wikipedia

Fact sheet

Beta
Vitamin B 12 deficiency

Other names

Hypocobalaminemia, cobalamin deficiency

Image of the cervical spinal cord in vitamin B 12 deficiency showing subacute combined degeneration. (A) The midsagittal T2 weighted image shows linear hyperintensity in the posterior portion of the cervical tract of the spinal cord (black arrows). (B) Axial T2 weighted images reveal the selective involvement of the posterior columns.

Symptoms

Decreased ability to think, feeling tired, depression, irritability, abnormal sensations, changes in reflexes

Complications

Megaloblastic anemia, irreversible damage to the brain and nervous system

Causes

Poor absorption, decreased intake, increased requirements

Diagnostic method

Blood levels below 148–185 pmol/L (200–250 pg/mL) in adults

Prevention

Supplementation in those at high risk

Treatment

Supplementation by mouth or injection

Frequency

6% (< 60 years old), 20% (> 60 years old)