peptides for pigmentation - PrivacyWall

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https://www.coeginpharma.com/en/our-research/projects/skin-pigmen...

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Skin pigmentation | Coegin Pharma

NPP-4 is our skin pigmentation project. We plan to launch a self-tanning product based on NPP-4 in 2026, ... It is one of four pigmentation peptides. Subscribe. Receive press releases and reports to your e-mail. Coegin Pharma AB. Registration number 559078-0465. Address Coegin ...

https://pmc.ncbi.nlm.nih.gov/articles/PMC7555855/

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Up- or Downregulation of Melanin Synthesis Using Amino Acids, Peptides ...

The major targets of amino acids, peptides, and their analogs for the control of skin pigmentation. Microphthalmia-associated transcription factor (MITF) plays a primary role in inducing gene expression of melanogenic enzymes, such as tyrosinase (TYR), tyrosinase-related protein 1 (TYRP1), and dopachrome tautomerase (DCT) in response to various internal and external stimuli.

https://www.cosmeticsandtoiletries.com/cosmetic-ingredients/activ...

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Lightening Skin Through a Melanogenesis-interrupting Peptide

Cutaneous pigmentation is determined by melanogenesis, the transfer of melanosomes to keratinocytes, and the distribution of melanin to skin, among other processes. Interrupting these would limit skin pigmentation to achieve a better skin lightening effect. Here, the authors review the biological mechanisms of melanin production, then test a peptide designed to act on them for a lightening effect.

https://pubmed.ncbi.nlm.nih.gov/39896936/

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Peptide Design for Enhanced Anti-Melanogenesis: Optimizing ... - PubMed

Melanogenesis is a biochemical process that regulates skin pigmentation, which is crucial role in protecting against ultraviolet radiation. It is also associated with hyperpigmentation conditions such as melasma and age spots, which negatively impact aesthetics and self-confidence. Tyrosinase (TYR), …

https://www.tandfonline.com/doi/full/10.2147/DDDT.S500004

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Full article: Peptide Design for Enhanced Anti-Melanogenesis ...

Second, peptides reduce the activity of these enzymes, lowering their capacity to catalyze the transformation of L-tyrosine substrate into melanin. In efforts to reduce melanin production at the gene transcription level, the MITF transcription factor has become the primary target of anti-hyperpigmentation peptides.

https://lpi.oregonstate.edu/mic/health-disease/skin-health/peptid...

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Peptides and Skin Health - Linus Pauling Institute

Peptide fragments of α-melanocyte stimulating hormone (MSH) are capable of stimulating production of the skin pigment melanin, potentially increasing photoprotection in the skin. (More information) Due to their influence on collagen homeostasis , bioactive peptides are being investigated for their ability to treat aged and photoaged skin.

https://www.dovepress.com/peptide-design-for-enhanced-anti-melano...

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Peptide Design for Enhanced Anti-Melanogenesis: Optimizing Molecular ...

In efforts to reduce melanin production at the gene transcription level, the MITF transcription factor has become the primary target of anti-hyperpigmentation peptides. 49–51 Alcalase ®-hydrolyzed sericin peptide suppresses melanogenesis by reducing MITF expression through decreased pCREB/CREB levels without affecting the GSK3β/β-catenin ...

https://academic.oup.com/bjd/article/181/1/e11/6747171

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Antimelanogenic peptides | British Journal of Dermatology - Oxford Academic

Peptides are increasingly being used in skincare products as active ingredients and antimelanogenic (anti melanin) peptides are potentially useful for the treatment of hyperpigmentation. Alpha‐melanocyte stimulating hormone (alpha‐MSH) is a peptide that, through a complex sequence of events, is involved in the synthesis ‐ or production ‐ of melanin.

https://www.prevention.com/beauty/skin-care/g45158597/best-peptid...

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20 Best Peptide Serums of 2024, According to Dermatologists - Prevention

Peptide serum can benefit the skin. ... Best peptide serum for hyperpigmentation. Obagi Medical Professional-C Peptide Complex . $125 at Amazon. $125 at Walmart $73 at fragrancenet.com.

https://link.springer.com/article/10.1007/s13555-022-00748-4

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Effect of Reducing Pigmentation by Collagen Peptide Intake: A ...

Introduction We examined the effect of 5.0 g/day of collagen peptide (CP) or collagen peptide fermented with Aspergillus sojae (FCP) on skin pigmentation in healthy participants. Methods In this randomized, double-blind, placebo-controlled study, 44 men and women aged 25–63 years were placed into three groups by stratified random allocation and treated with CP, FCP, or placebo (PL) at 5.0 g ...

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